Alzforum highlight: Tenvie brain-penetrant NLRP3 inhibitor reverses hypothalamic inflammation to drive weight loss in obesity

As featured by Alzforum, Tenvie's research preprint showcases how our brain-penetrant NLRP3 inhibitor, TN-783, alleviates inflammation-driven microglial activation, allowing the hypothalamus to more appropriately regulate food intake. This restoration of metabolic control results in gradual, fat-preferring weight loss in obese mice.

Read the full article on Alzforum here!